Cincinnati rookie running back Rodney Anderson is believed to have torn his right ACL on Thursday night in the Bengals’ final preseason game, according to multiple reports.

The reports added he likely will miss the season. He left the game, a 13-6 loss to the Indianapolis Colts, in the first quarter after a four-yard run.

Doctors had just cleared Anderson to play three weeks ago, and he has a history of serious injuries.

Anderson, a sixth-round draft selection, sustained the same injury last season with Oklahoma.

In 2015, his first season with the Sooners, he sustained a broken leg. The following year, he broke a bone in his neck, and last season, the torn ACL ended his campaign in Week 2.

He played in just 17 games in four years in Oklahoma. In 2017, he played in 13 games, gaining 1,442 yards from scrimmage and scoring 21 touchdowns.

The Bengals drafted him to back up running backs Giovani Bernard and Joe Mixon, the latter his former Sooners teammate. In the third preseason game, he had four catches for 51 yards.

The Bengals also drafted Trayveon Williams from Texas A&M in the sixth round of the 2019 draft.