New Zealand host Australia at fortress Eden Park looking for a first win in three Tests to retain the Bledisloe Cup.
Dan Biggar, James Davies and Jake Ball come into the Wales side as they eye revenge against England in Cardiff.
Australia have made one change to their starting team to face the All Blacks, with Adam Coleman replacing Rory Arnold.
Centre Duncan Taylor will make a timely Scotland comeback against France, five weeks before the Rugby World Cup starts.
Attack consultant Swys de Bruin has left his role with the Springboks for "personal and medical reasons."