After the Chiefs came back to defeat the Crusaders in Hamilton, the Blues overpowered the Waratahs and claimed a bonus point.
There were reports Saracens faced expulsion from the European Champions Cup, but the holders have been hit with a fine.
Captain Stuart Hogg is confident Scotland can let their rugby do the talking and beat England to retain the Calcutta Cup.
Arthur Vincent and Jayden Hayward come into the France and Italy starting line-ups respectively for the match in Paris.
Saracens will discover in London on Friday whether they will face any action for picking Titi Lamositele against Racing 92.
Irae Simone set the ball rolling for the battling Brumbies in a fine win over the Rebels, while the Sharks dazzled against the Highlanders.
After both recorded opening wins, Ireland and Wales clash in Dublin. Meanwhile, there's the small matter of a Calcutta Cup clash.
With Brad Mooar heading off to be part of New Zealand's coaching staff, Glenn Delaney will take over as head coach of the Scarlets.
Gregor Townsend will consider Finn Russell's involvement in the Six Nations after the Calcutta Cup clash on Saturday.
Scotland have resisted the temptation to make sweeping changes for the Calcutta Cup contest with England.